Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10967025 | 0.75 | CHRM2 (0.30) | — | |
| SCHEMBL818755 | 0.75 | TSHR (0.48) | TSHRRAB9AALDH1A1LMNA | |
| SCHEMBL11114301 | 0.74 | — | — | |
| SCHEMBL11041098 | 0.74 | NAAA (0.40) | TSHRALDH1A1EPHX2 | |
| SCHEMBL10934698 | 0.74 | RAB9A (0.33) | TSHRRAB9AALDH1A1 | |
| SCHEMBL293438 | 0.73 | TSHR (0.39) | TSHRRAB9AALDH1A1LMNAEPHX2 | |
| SCHEMBL16885806 | 0.72 | TSHR (0.45) | TSHRRAB9AALDH1A1LMNA | |
| SCHEMBL31675156 | 0.70 | TSHR (0.43) | TSHRRAB9AALDH1A1LMNA | |
| SCHEMBL2946396 | 0.69 | TSHR (0.42) | TSHRRAB9AALDH1A1 | |
| SCHEMBL11038560 | 0.68 | EPHX1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038271-B1 | CYCLOPROPANE CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND USE IN COMBATING PARASITES OF PLANTS AND ANIMALS, THEIR COMPOSITIONS AND INTERMEDIATES | ROUSSEL-UCLAF (FR) | 1984-07-04 | — | — | EP | disclosed |
| EP-0038271-A2 | Cyclopropane carboxylic acid derivatives, their preparation and use in combating parasites of plants and animals, their compositions and intermediates | ROUSSEL-UCLAF (FR) | 1981-10-21 | — | — | EP | disclosed |