Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 8/20 | 0.52 |
| ▸ | CES1 | P23141 | 7/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMO | O15229 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.44 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3623156 | 0.98 | CES2 (0.50) | CES2CES1POLBELANEHPGD | |
| SCHEMBL14614307 | 0.91 | CES2 (0.56) | CES2CES1POLBELANENPC1 | |
| SCHEMBL17779987 | 0.83 | KMO (0.50) | HPGDKMOKCNK3KCNK9 | |
| SCHEMBL16109370 | 0.79 | KMT2A (0.54) | CES2CES1POLBLMNANPC1 | |
| SCHEMBL27566019 | 0.79 | POLB (0.47) | CES2CES1POLBELANEHPGD | |
| SCHEMBL965420 | 0.78 | SRD5A2 (0.63) | POLBELANEHPGDMCL1 | |
| Benzoic Acid SCHEMBL31356467 | 0.78 | SRD5A2 (0.58) | CES2CES1POLBELANEHPGD | |
| Benzoic Acid SCHEMBL5788950 | 0.78 | SRD5A2 (0.58) | CES2CES1POLBELANEHPGD | |
| SCHEMBL15967650 | 0.77 | SLC18A3 (0.45) | CES2CES1POLBELANEMCL1 | |
| SCHEMBL8194107 | 0.77 | PBRM1 (0.46) | CES2CES1POLBLMNAKMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | claimed |