Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.58 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035202 | 0.86 | HPGD (0.58) | HPGDPDE5AGAAPKMTLR9 | |
| SCHEMBL27801622 | 0.86 | HPGD (0.58) | HPGDPDE5AGAAPKMTLR9 | |
| SCHEMBL10744425 | 0.79 | HPGD (0.65) | HPGDPDE5AGAAPKMTLR9 | |
| SCHEMBL4304620 | 0.79 | NOTUM (0.61) | HPGDPDE5AL3MBTL1ATMTDP1 | |
| SCHEMBL9834928 | 0.79 | PDE5A (0.54) | HPGDPDE5AL3MBTL1ATMTDP1 | |
| SCHEMBL9667595 | 0.78 | ALDH1A1 (0.47) | HPGDPDE5AGAAL3MBTL1ATM | |
| SCHEMBL28037987 | 0.77 | HPGD (0.61) | HPGDPDE5AGAAPKMTLR9 | |
| SCHEMBL16110543 | 0.76 | OPRK1 (0.65) | HPGDGAAPKMTLR9L3MBTL1 | |
| SCHEMBL2343941 | 0.76 | HPGD (0.65) | HPGDPDE5AGAAPKMTLR9 | |
| SCHEMBL24091884 | 0.75 | NPC1 (0.43) | HPGDL3MBTL1ATMTDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59167548-A | — | — | None | — | — | JP | disclosed |
| JP-S59167548-A | 5-BENZOYL-2-ANILINO SUBSTITUTED-PHENYLACETIC ACID DERIVATIVE | HOKURIKU SEIYAKU CO LTD | 1984-09-21 | — | — | JP | disclosed |