Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866003 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL29776250 | 0.82 | ALDH1A1 (0.62) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL28356761 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8755086 | 0.79 | MAPT (0.49) | MAPTALDH1A1TDP1TSHRLMNA | |
| SCHEMBL176879 | 0.79 | ALDH1A1 (0.51) | MAPTALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL204041 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL8606960 | 0.79 | MAPT (0.58) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL27774544 | 0.79 | ALDH1A1 (0.61) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL5090260 | 0.77 | NR4A1 (0.61) | MAPTALDH1A1TDP1MEN1KMT2A | |
| SCHEMBL11420051 | 0.77 | MAPT (0.62) | MAPTALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | claimed |
| US-4472308-A | Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group | ICI UNITED STATES, INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4225491-A | REACTIVE DYES FOR COTTON | ICI UNITED STATES, INC. (US) | 1980-09-30 | — | — | US | disclosed |