Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL178068 | 0.80 | ALDH1A1 (0.61) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL8755086 | 0.79 | MAPT (0.49) | ALDH1A1TSHRMAPTMAPK1HPGD | |
| SCHEMBL28356761 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPTKMT2AMEN1NPSR1 | |
| SCHEMBL11037844 | 0.79 | MAPT (0.55) | ALDH1A1TSHRCYP3A4MAPTKMT2A | |
| SCHEMBL177217 | 0.77 | ALDH1A1 (0.53) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL25230829 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL17368518 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL3721960 | 0.76 | MAPT (0.64) | ALDH1A1TSHRCYP3A4RECQLMAPT | |
| SCHEMBL4237009 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 | |
| SCHEMBL12031432 | 0.76 | ALDH1A1 (0.51) | ALDH1A1TSHRCYP3A4RECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110251418-A1 | CASR AGONISTS | AJINOMOTO CO., INC. (JP) | 2011-10-13 | — | — | US | disclosed |
| EP-2345636-A1 | CASR AGONIST | Ajinomoto Co., Inc. (JP) | 2011-07-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110251418-A1 | CASR AGONISTS | CASR, GIPR, GRIK5 | ALDH1A1 2705/4885TSHR 481/4885CYP3A4 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.