Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | FNTA | P49354 | 3/20 | 0.58 |
| ▸ | FNTB | P49356 | 3/20 | 0.58 |
| ▸ | NR3C1 | P04150 | 6/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.57 |
| ▸ | PGR | P06401 | 4/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.55 |
| ▸ | AR | P10275 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038015 | 1.00 | KMT2A (0.72) | KMT2AFNTAFNTBNR3C1HIF1A | |
| SCHEMBL11038901 | 1.00 | KMT2A (0.72) | KMT2AFNTAFNTBNR3C1HIF1A | |
| Meprednisone SCHEMBL19327148 | 0.88 | HSD17B10 (0.70) | KMT2AFNTAFNTBNR3C1HIF1A | |
| Meprednisone SCHEMBL20856991 | 0.88 | HSD17B10 (0.70) | KMT2AFNTAFNTBNR3C1HIF1A | |
| Meprednisone SCHEMBL5483442 | 0.88 | HSD17B10 (0.70) | KMT2AFNTAFNTBNR3C1HIF1A | |
| Meprednisone SCHEMBL11846862 | 0.88 | HSD17B10 (0.70) | KMT2AFNTAFNTBNR3C1HIF1A | |
| Meprednisone SCHEMBL9512 | 0.88 | HSD17B10 (0.70) | KMT2AFNTAFNTBNR3C1HIF1A | |
| SCHEMBL12396812 | 0.88 | KMT2A (0.56) | KMT2AFNTAFNTBNR3C1HIF1A | |
| SCHEMBL11689686 | 0.87 | KMT2A (0.71) | KMT2AFNTAFNTBNR3C1HIF1A | |
| SCHEMBL25932838 | 0.86 | NR3C1 (0.60) | KMT2AFNTAFNTBNR3C1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0057401-B1 | AROMATIC HETEROCYCLIC ESTERS OF STEROIDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SCHERING CORPORATION (US) | 1984-08-01 | — | — | EP | disclosed |
| US-4124707-A | 7α-Halogeno-3,20-dioxo-1,4-pregnadienes, methods for their manufacture, their use as anti-inflammatory agents, and pharmaceutical formulations useful therefor | SCHERING CORPORATION (US) | 1978-11-07 | — | — | US | disclosed |