Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 5/20 | 0.48 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | GALR2 | O43603 | 1/20 | 0.42 |
| ▸ | FBP1 | P09467 | 2/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038251 | 1.00 | VCP (0.48) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL3221423 | 0.80 | VCP (0.47) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL3230555 | 0.80 | VCP (0.47) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL8464220 | 0.77 | MTNR1A (0.46) | ALDH1A1MTNR1AMTNR1BTUBB4ATUBB | |
| SCHEMBL4384056 | 0.76 | MEN1 (0.47) | LMNAMAPTNPSR1ALDH1A1HTT | |
| SCHEMBL8709084 | 0.74 | MAPT (0.66) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL20561887 | 0.74 | PRMT1 (0.55) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL20561884 | 0.74 | PRMT1 (0.55) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL31618276 | 0.74 | MAPT (0.66) | VCPPRMT1LMNAMAPTNPSR1 | |
| SCHEMBL8709081 | 0.74 | MAPT (0.66) | VCPPRMT1LMNAMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0162695-A1 | 6-Oxygenated-1,3,,4,5-Tetrahydrobenz(cd)indol-4-amines | SMITHKLINE BEECHAM CORPORATION (US) | 1985-11-27 | — | — | EP | disclosed |