SCHEMBL11038432

SCHEMBL11038432

Cc1c(O)c(Cl)cc(Cl)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 9/20 0.52
HPGD P15428 7/20 0.52
TSHR P16473 6/20 0.52
MAPK1 P28482 3/20 0.52
CYP3A4 P08684 5/20 0.50
RECQL P46063 3/20 0.50
TTR P02766 3/20 0.50
ALDH1A1 P00352 3/20 0.50
CASP1 P29466 2/20 0.50
THRB P10828 3/20 0.46
SIRT1 Q96EB6 1/20 0.45
ALOX15 P16050 5/20 0.44
SMN1; SMN2 Q16637 4/20 0.44
HIF1A Q16665 4/20 0.44
CYP2C19 P33261 3/20 0.44
ALOX12 P18054 3/20 0.44
MAPT P10636 3/20 0.44
CHRM1 P11229 3/20 0.44
TBXA2R P21731 3/20 0.44
ADRA1A P35348 3/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25828290 0.88 HSD17B10 (0.48) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL13997274 0.86 HSD17B10 (0.59) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL27557989 0.86 SIRT1 (0.45) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL24727674 0.82 HSD17B10 (0.40) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL21186739 0.82 HSD17B10 (0.42) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL6678885 0.80 HSD17B10 (0.43) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL10771021 0.80 HSD17B10 (0.59) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL21614379 0.78 TPMT (0.43) HSD17B10HPGDTSHRMAPK1CYP3A4
SCHEMBL20607316 0.77 ERN1 (0.59) HSD17B10ALDH1A1ALOX15SMN1; SMN2HIF1A
SCHEMBL9040690 0.77 TTR (0.48) HSD17B10HPGDTSHRMAPK1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1614003-B1 PHOTOGRAPHIC COLOUR MATERIAL CONTAINING A RESORCINOL DERIVATIVE AS BLACK COUPLER FUJIFILM CORP (JP) 2008-02-27 EP disclosed
EP-0039807-B1 HAIR-DYEING COMPOSITIONS Henkel Kommanditgesellschaft auf Aktien (DE) 1984-02-15 EP disclosed
EP-0039807-A2 Hair-dyeing compositions Henkel Kommanditgesellschaft auf Aktien (DE) 1981-11-18 EP disclosed
EP-0039807-A2 Hair-dyeing compositions Henkel Kommanditgesellschaft auf Aktien (DE) 1981-11-18 EP disclosed