Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10820981 | 0.81 | HSD17B10 (0.46) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL25828290 | 0.81 | HSD17B10 (0.48) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL11038432 | 0.80 | HSD17B10 (0.52) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL26018812 | 0.79 | HSD17B10 (0.43) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL22454878 | 0.79 | HSD17B10 (0.43) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL11384008 | 0.79 | HSD17B10 (0.52) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL28126392 | 0.77 | HSD17B10 (0.42) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL212921 | 0.77 | HSD17B10 (0.55) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL9579920 | 0.75 | HSD17B10 (0.46) | HSD17B10TSHRHPGDCYP3A4ALDH1A1 | |
| SCHEMBL5463498 | 0.75 | SELL (0.50) | HSD17B10HPGDCYP3A4ALDH1A1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004047925-A2 | THERAPEUTIC OXIDATION CATALYSTS | EXETER ANTIOXIDANT THERAPEUTICS LIMITED (GB) | 2004-06-10 | — | — | WO | disclosed |