Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5026910 | 0.83 | TAAR1 (0.52) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL23049820 | 0.78 | NR3C1 (0.48) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL26931370 | 0.77 | TAAR1 (0.50) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL23211227 | 0.77 | TAAR1 (0.55) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL15701930 | 0.76 | TAAR1 (0.46) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL4178223 | 0.76 | TAAR1 (0.46) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL4169345 | 0.76 | TAAR1 (0.46) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL4161045 | 0.76 | TAAR1 (0.46) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL5293772 | 0.76 | TAAR1 (0.46) | TAAR1NR3C1NR3C2POLBALDH1A1 | |
| SCHEMBL28114432 | 0.74 | TAAR1 (0.45) | TAAR1NR3C1NR3C2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |