Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4169345 | 1.00 | TAAR1 (0.46) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL4178223 | 1.00 | TAAR1 (0.46) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL23049820 | 0.82 | NR3C1 (0.48) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL5026910 | 0.79 | TAAR1 (0.52) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL5696571 | 0.79 | TAAR1 (0.48) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL9116596 | 0.79 | ACHE (0.46) | ALDH1A1CYP3A4 | |
| SCHEMBL15840454 | 0.78 | ALOX15 (0.41) | TRPA1LMNACHRM1SLC6A2ADRA1A | |
| SCHEMBL20651209 | 0.78 | TAAR1 (0.43) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL21131786 | 0.78 | TAAR1 (0.43) | TAAR1NR3C1NR3C2TSHRNPC1 | |
| SCHEMBL21131600 | 0.76 | TAAR1 (0.39) | TAAR1NR3C1NR3C2TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090163601-A1 | (R)-2-METHYL-(2,5-DIMETHYLPHENYL)PROPANOL AND (S)-(2-METHYL-2,5-DIMETHYLPHENYL)PROPANOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-25 | — | — | US | claimed |
| US-20090163601-A1 | (R)-2-METHYL-(2,5-DIMETHYLPHENYL)PROPANOL AND (S)-(2-METHYL-2,5-DIMETHYLPHENYL)PROPANOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-25 | — | — | US | disclosed |
| US-20090163601-A1 | (R)-2-METHYL-(2,5-DIMETHYLPHENYL)PROPANOL AND (S)-(2-METHYL-2,5-DIMETHYLPHENYL)PROPANOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090163601-A1 | (R)-2-METHYL-(2,5-DIMETHYLPHENYL)PROPANOL AND (S)-(2-METHYL-2,5-DIMETHYLPHENYL)PROPANOL | ADRB2, PNMT, DRD4 | TAAR1 1746/4885NR3C1 444/4885NR3C2 27/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.