Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 3/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7349267 | 0.83 | HSD11B1 (0.36) | SLC9A1KDM1ARCOR1ALDH1A1HPGD | |
| SCHEMBL21037775 | 0.73 | KDM1A (0.36) | SLC9A1KDM1ARCOR1ALDH1A1MAPT | |
| SCHEMBL7313249 | 0.66 | FBP1 (0.36) | ALDH1A1MAPTHPGD | |
| SCHEMBL4337871 | 0.65 | KDM1A (0.44) | SLC9A1KDM1ARCOR1ALDH1A1MAPT | |
| SCHEMBL13992539 | 0.58 | HTR2A (0.41) | SLC9A1KDM1ARCOR1ALDH1A1MAPT | |
| SCHEMBL3790442 | 0.58 | CYP3A4 (0.35) | KDM1AALDH1A1MAPT | |
| SCHEMBL2349000 | 0.57 | CYP1A2 (0.56) | — | |
| SCHEMBL2349002 | 0.57 | CYP1A2 (0.56) | — | |
| SCHEMBL11044547 | 0.57 | IDO1 (0.46) | ALDH1A1 | |
| SCHEMBL11044550 | 0.57 | IDO1 (0.46) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |