Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11038949 | 1.00 | ABCG2 (0.39) | ABCG2ALDH1A1KDM4ECISD1EGFR | |
| SCHEMBL11343843 | 0.84 | ABCG2 (0.41) | ABCG2ALDH1A1KDM4ECISD1EGFR | |
| SCHEMBL10935864 | 0.84 | ABCG2 (0.41) | ABCG2ALDH1A1KDM4ECISD1EGFR | |
| SCHEMBL2017583 | 0.79 | GSK3B (0.44) | ABCG2CISD1EGFRLMNA | |
| SCHEMBL11042783 | 0.79 | ABCG2 (0.56) | ABCG2ALDH1A1KDM4E | |
| SCHEMBL11042787 | 0.79 | ABCG2 (0.56) | ABCG2ALDH1A1KDM4E | |
| SCHEMBL11040732 | 0.72 | ABCG2 (0.56) | ABCG2ALDH1A1KDM4EEGFR | |
| SCHEMBL11040729 | 0.72 | ABCG2 (0.56) | ABCG2ALDH1A1KDM4EEGFR | |
| SCHEMBL11248486 | 0.72 | CISD1 (0.39) | ALDH1A1KDM4ECISD1EGFRLMNA | |
| SCHEMBL9568614 | 0.72 | ABCG2 (0.56) | ABCG2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028511-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND MICROORGANISMS CAPABLE OF THEIR PRODUCTION | GLAXO GROUP LIMITED (GB) | 1984-04-11 | — | — | EP | disclosed |
| US-4410626-A | Process for the production of 7α-methoxycephalosporin derivatives | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1983-10-18 | — | — | US | disclosed |
| US-4379920-A | CEPHAMYCIN DERIVATIVE | GLAXO GROUP LIMITED (GB) | 1983-04-12 | — | — | US | disclosed |
| US-4259326-A | ANTIBIOTICS, BACTERICIDES | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1981-03-31 | — | — | US | disclosed |