Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.47 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | ABL2 | P42684 | 1/20 | 0.43 |
| ▸ | IAPP | P10997 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SRC | P12931 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040732 | 1.00 | ABCG2 (0.56) | ABCG2TTRAPPPTPN1TUBB1 | |
| SCHEMBL11138976 | 0.82 | ABCG2 (0.59) | ABCG2TTRAPPPTPN1TUBB1 | |
| SCHEMBL11138973 | 0.82 | ABCG2 (0.59) | ABCG2TTRAPPPTPN1TUBB1 | |
| SCHEMBL11042787 | 0.82 | ABCG2 (0.56) | ABCG2KDM4ECA12CA1CA2 | |
| SCHEMBL11042783 | 0.82 | ABCG2 (0.56) | ABCG2KDM4ECA12CA1CA2 | |
| SCHEMBL5375473 | 0.73 | APP (0.54) | ABCG2TTRAPPTUBB1RAB9A | |
| SCHEMBL5395111 | 0.73 | APP (0.54) | ABCG2TTRAPPTUBB1RAB9A | |
| SCHEMBL11038949 | 0.72 | ABCG2 (0.39) | ABCG2EGFRKDM4EALDH1A1 | |
| SCHEMBL11038951 | 0.72 | ABCG2 (0.39) | ABCG2EGFRKDM4EALDH1A1 | |
| SCHEMBL9347097 | 0.71 | DNM1 (0.72) | DNM1EGFRKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0028511-B1 | CEPHALOSPORINS, PROCESSES FOR THEIR PREPARATION AND MICROORGANISMS CAPABLE OF THEIR PRODUCTION | GLAXO GROUP LIMITED (GB) | 1984-04-11 | — | — | EP | disclosed |
| US-4379920-A | CEPHAMYCIN DERIVATIVE | GLAXO GROUP LIMITED (GB) | 1983-04-12 | — | — | US | disclosed |
| EP-0028511-A1 | Cephalosporins, processes for their preparation and microorganisms capable of their production | GLAXO GROUP LIMITED (GB) | 1981-05-13 | — | — | EP | disclosed |