SCHEMBL9568614

SCHEMBL9568614

COC(=O)C(=Cc1ccc(OC)cc1)OC

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 2/20 0.56
ALDH1A1 P00352 4/20 0.52
MAPT P10636 3/20 0.52
KDM4E B2RXH2 2/20 0.52
HPGD P15428 2/20 0.52
GSK3B P49841 1/20 0.51
HDAC3 O15379 1/20 0.50
HDAC1 Q13547 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50
HDAC6 Q9UBN7 1/20 0.50
F3 P13726 1/20 0.50
CYP1A2 P05177 2/20 0.49
CYP3A4 P08684 2/20 0.49
TSHR P16473 1/20 0.49
NFKB1 P19838 1/20 0.49
APEX1 P27695 1/20 0.49
BLM P54132 1/20 0.49
PMP22 Q01453 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18704227 1.00 ABCG2 (0.56) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL28756428 0.86 ABCG2 (0.48) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL19078491 0.85 ABCG2 (0.56) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL28947529 0.85 ABCG2 (0.56) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL6123027 0.85 ABCG2 (0.56) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL11242541 0.85 GSK3B (0.49) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL1685991 0.85 ABCG2 (0.50) ABCG2ALDH1A1MAPTKDM4EHPGD
SCHEMBL9369366 0.83 ALDH1A1 (0.53) ABCG2ALDH1A1CYP2A6
SCHEMBL77601 0.83 MAPT (0.53) ALDH1A1MAPTKDM4EHPGDGSK3B
SCHEMBL5606962 0.83 ABCG2 (0.61) ABCG2ALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114341246-A Use of a phenol-substituted sugar derivative as a stabilizer, a plastic composition, a method of stabilizing a plastic material and a phenol-substituted sugar derivative 弗劳恩霍夫应用研究促进协会 2022-04-12 CN disclosed
EP-0567430-A1 Substituted 1-Hydroxy-2,6-Diaryl-4-Piperidone Ketal Stabilizers CIBA-GEIGY AG (CH) 1993-10-27 EP disclosed