Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.35 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5236657 | 0.86 | MTNR1A (0.54) | HTR1AMTNR1A | |
| SCHEMBL13534203 | 0.82 | AOC3 (0.54) | HTR1AMTNR1AABCG2KMT2AAOC3 | |
| SCHEMBL27443068 | 0.81 | ALDH1A1 (0.45) | HTR1AMTNR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL1145696 | 0.79 | ABCG2 (0.44) | HTR1AMTNR1AABCG2KMT2ATDP1 | |
| SCHEMBL4309152 | 0.79 | MTNR1A (0.48) | HTR1AMTNR1AABCG2KMT2ATDP1 | |
| SCHEMBL9239494 | 0.79 | MTNR1A (0.47) | HTR1AMTNR1AABCG2KMT2ATDP1 | |
| SCHEMBL25335293 | 0.78 | HTR1B (0.46) | HTR1AMTNR1AABCG2KMT2ATDP1 | |
| SCHEMBL13533388 | 0.78 | TP53 (0.44) | HTR1AMTNR1AABCG2KMT2ATDP1 | |
| SCHEMBL13534270 | 0.78 | MTNR1A (0.50) | HTR1AMTNR1AKMT2ATDP1L3MBTL1 | |
| SCHEMBL17274865 | 0.78 | MAPT (0.44) | HTR1AMTNR1AABCG2KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4487772-A | CARDIOTONIC AGENTS | OTSUKA PHARMACEUTICAL CO. LTD. (JP) | 1984-12-11 | — | — | US | disclosed |
| US-4468402-A | Carbostyril derivatives, process for producing the same and cardiotonic compositions containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454130-A | CARDIOTONIC, HYPOTENSIVE AGENTS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1984-06-12 | — | — | US | disclosed |