SCHEMBL11039385

SCHEMBL11039385

Nc1cc(P(=O)(O)O)ccc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.38
CA4 P22748 2/20 0.38
CA5A P35218 2/20 0.38
FBP1 P09467 7/20 0.36
ALDH1A1 P00352 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
ALOX15 P16050 1/20 0.35
CYP2C19 P33261 1/20 0.35
GRM2 Q14416 1/20 0.35
PGK1 P00558 3/20 0.34
PGK2 P07205 3/20 0.34
GRIK1 P39086 1/20 0.33
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA6 P23280 1/20 0.31
CA7 P43166 1/20 0.31
CA9 Q16790 1/20 0.31
CA14 Q9ULX7 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26602790 0.83 CA2 (0.44) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL5004888 0.80 CA2 (0.42) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL10781577 0.80 CA2 (0.42) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL11042057 0.77 GAA (0.47) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL11037804 0.75 TDP1 (0.48) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL12002753 0.75 TDP1 (0.47) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL11039147 0.75 CA2 (0.48) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL8772914 0.72 CA2 (0.39) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL31236948 0.72 CA2 (0.39) CA2CA4CA5AFBP1ALDH1A1
SCHEMBL8613678 0.71 HPGD (0.43) CA2CA4CA5AFBP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US claimed
US-4472308-A Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group ICI UNITED STATES, INC. (US) 1984-09-18 US disclosed
US-4230618-A CELLULOSE ICI UNITED STATES, INC. (US) 1980-10-28 US disclosed
US-4225491-A REACTIVE DYES FOR COTTON ICI UNITED STATES, INC. (US) 1980-09-30 US disclosed