Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CASP1 | P29466 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.46 |
| ▸ | FBP1 | P09467 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002753 | 0.83 | TDP1 (0.47) | TDP1MAPTALDH1A1TSHRCYP3A4 | |
| SCHEMBL10781577 | 0.80 | CA2 (0.42) | TDP1MAPTALDH1A1TSHRCYP3A4 | |
| SCHEMBL3347914 | 0.80 | ALDH1A1 (0.46) | TDP1ALDH1A1TSHRFBP1LMNA | |
| SCHEMBL664342 | 0.78 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRFBP1LMNA | |
| Hydrochloric Acid SCHEMBL10917756 | 0.78 | ALDH1A1 (0.44) | TDP1ALDH1A1TSHRFBP1LMNA | |
| SCHEMBL11042057 | 0.77 | GAA (0.47) | TDP1MAPTALDH1A1TSHRFBP1 | |
| SCHEMBL11039385 | 0.75 | CA2 (0.38) | TDP1ALDH1A1FBP1CA2CA4 | |
| SCHEMBL8613678 | 0.75 | HPGD (0.43) | TDP1ALDH1A1TSHRFBP1LMNA | |
| SCHEMBL2669738 | 0.75 | CYP3A4 (0.43) | TDP1MAPTALDH1A1TSHRCYP3A4 | |
| SCHEMBL11039147 | 0.75 | CA2 (0.48) | TDP1ALDH1A1TSHRFBP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | claimed |
| US-4472308-A | Azo dyestuffs containing an amino or acylated amino naphthol monosulfonic acid radical and at least one reactive phosphoric or phosphonic acid group | ICI UNITED STATES, INC. (US) | 1984-09-18 | — | — | US | disclosed |
| US-4230618-A | CELLULOSE | ICI UNITED STATES, INC. (US) | 1980-10-28 | — | — | US | disclosed |
| US-4225491-A | REACTIVE DYES FOR COTTON | ICI UNITED STATES, INC. (US) | 1980-09-30 | — | — | US | disclosed |