Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | WNT1 | P04628 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26095936 | 0.91 | ALDH1A1 (0.56) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL11039671 | 0.88 | SMN1; SMN2 (0.59) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL274448 | 0.88 | SMN1; SMN2 (0.59) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL12482578 | 0.86 | CHRM1 (0.59) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL14311961 | 0.86 | SMN1; SMN2 (0.57) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4788803 | 0.86 | SMN1; SMN2 (0.57) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL19066091 | 0.85 | CHRM1 (0.47) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL28944872 | 0.85 | CHRM1 (0.51) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL1999076 | 0.84 | CHRM1 (0.57) | CHRM1ALDH1A1SMN1; SMN2GAAL3MBTL1 | |
| SCHEMBL3091613 | 0.82 | ALDH1A1 (0.64) | CHRM1ALDH1A1SMN1; SMN2L3MBTL1L3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399312-A1 | SUBSTITUTED PYRIMIDINES AND METHODS OF USE | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2023-12-14 | — | — | US | disclosed |
| EP-4234031-A2 | C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS | Revolution Medicines, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-1345899-B1 | N-substituted amides as NK1 receptor antagonists | ASTRAZENECA AB (SE) | 2009-01-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399312-A1 | SUBSTITUTED PYRIMIDINES AND METHODS OF USE | ALK, TYMP, ENTPD5 | CHRM1 3609/4885ALDH1A1 2596/4885SMN1; SMN2 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.