Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | GSK3B | P49841 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2261141 | 0.91 | PTPN1 (0.66) | PARP10PTPN1GSK3BKMT2AALDH1A1 | |
| SCHEMBL2570730 | 0.84 | PTPN1 (0.56) | PARP10PTPN1GSK3BKMT2AALDH1A1 | |
| SCHEMBL4324217 | 0.83 | GSK3B (0.72) | PARP10PTPN1GSK3BKMT2AALDH1A1 | |
| SCHEMBL11037438 | 0.83 | ELANE (0.53) | PTPN1GSK3BKMT2AMAPTMEN1 | |
| SCHEMBL11038727 | 0.83 | ELANE (0.53) | PARP10PTPN1GSK3BKMT2AALDH1A1 | |
| SCHEMBL9663679 | 0.80 | PARP10 (0.81) | PARP10KMT2AALDH1A1PKMMAPT | |
| SCHEMBL2755026 | 0.80 | KMT2A (0.68) | PARP10KMT2AALDH1A1PKMMAPT | |
| SCHEMBL11039303 | 0.80 | PARP10 (0.60) | PARP10KMT2AALDH1A1PKMMAPT | |
| SCHEMBL16675183 | 0.79 | KMT2A (0.59) | PARP10KMT2AALDH1A1PKMMAPT | |
| SCHEMBL4333412 | 0.79 | PTPN1 (0.71) | PARP10PTPN1GSK3BKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0046144-B1 | THERAPEUTICALLY ACTIVE DERIVATIVES OF PHENYLETHANOL AMINES | Aktiebolaget Draco (SE) | 1984-04-11 | — | — | EP | disclosed |
| US-4442300-A | BRONCHOSPASMOLYTIC | AKTIEBOLAGET DRACO (SE) | 1984-04-10 | — | — | US | disclosed |
| EP-0046144-A1 | Therapeutically active derivatives of phenylethanol amines | Aktiebolaget Draco (SE) | 1982-02-17 | — | — | EP | disclosed |