SCHEMBL16675183

SCHEMBL16675183

O=C(Oc1ccc(OC(=O)c2ccccc2)cc1)Oc1cc(OC(=O)Oc2ccc(OC(=O)c3ccccc3)cc2)cc(C(=O)Oc2ccc(OC(=O)c3ccccc3)cc2)c1

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 10/20 0.59
MAPT P10636 4/20 0.59
TDP1 Q9NUW8 3/20 0.59
MEN1 O00255 3/20 0.59
PARP10 Q53GL7 1/20 0.59
ALDH1A1 P00352 2/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
PKM P14618 1/20 0.56
NSD2 O96028 1/20 0.54
RAB9A P51151 1/20 0.53
ALOX5 P09917 1/20 0.49
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
CASP3 P42574 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
POLB P06746 1/20 0.48
HSD17B10 Q99714 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16675188 0.96 KMT2A (0.62) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL2755026 0.87 KMT2A (0.68) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL725405 0.84 PARP10 (0.77) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL12649365 0.83 KMT2A (0.59) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL11039303 0.83 PARP10 (0.60) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL9663679 0.82 PARP10 (0.81) KMT2AMAPTTDP1MEN1PARP10
Hydrochloric Acid SCHEMBL16050040 0.82 PARP10 (0.74) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL28558841 0.82 TSHR (0.68) KMT2AMAPTTDP1MEN1PARP10
SCHEMBL12649366 0.81 ALOX5 (0.68) KMT2AMAPTMEN1ALDH1A1PKM
SCHEMBL8205435 0.81 PARP10 (0.78) KMT2AMAPTTDP1MEN1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed
US-20150114257-A1 METHOD OF PREPARING RETARDATION FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY Konica Minolta, Inc. (JP) 2015-04-30 US disclosed