Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GSK3B | P49841 | 4/20 | 0.50 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Beta-Naphtoic Acid SCHEMBL4328136 | 0.94 | PTPN1 (0.63) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL4328140 | 0.87 | PTPN1 (0.53) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL2261141 | 0.84 | PTPN1 (0.66) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL29411099 | 0.84 | PTPN1 (1.00) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL220588 | 0.84 | PTPN1 (1.00) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL418527 | 0.82 | MAPT (0.68) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL3292986 | 0.81 | PTPN1 (0.53) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL4324217 | 0.80 | GSK3B (0.72) | PTPN1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL4326711 | 0.80 | MAPT (0.60) | KMT2AMAPTMEN1TDP1CES2 | |
| SCHEMBL14206802 | 0.80 | NPC1 (0.62) | KMT2AMAPTMEN1TDP1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009146013-A1 | MYOSIN LIGHT CHAIN PHOSPHATASE INHIBITORS | GEORGETOWN UNIVERSITY (US) | 2009-12-03 | — | — | WO | disclosed |