SCHEMBL110398

SCHEMBL110398

Cc1ccc([N+](=O)[O-])cc1NCCO

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT2B Q92831 1/20 0.68
LMNA P02545 2/20 0.62
KMT2A Q03164 7/20 0.61
TSHR P16473 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 7/20 0.55
MEN1 O00255 4/20 0.55
MAPT P10636 3/20 0.55
GAA P10253 1/20 0.55
SMN1; SMN2 Q16637 3/20 0.54
HTT P42858 3/20 0.54
THRB P10828 1/20 0.54
HPGD P15428 3/20 0.53
PKM P14618 1/20 0.49
CYP1A2 P05177 1/20 0.48
CYP3A4 P08684 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
CYP2C19 P33261 1/20 0.48
KDM4E B2RXH2 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682978 0.88 KMT2A (0.65) KAT2BKMT2ATSHRTDP1ALDH1A1
SCHEMBL10489329 0.86 KAT2B (0.69) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL29390514 0.85 KMT2A (0.70) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL126989 0.85 KMT2A (0.70) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL8755425 0.85 KAT2B (0.53) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL8249825 0.84 KAT2B (0.81) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL2234808 0.84 KAT2B (0.63) KAT2BLMNAKMT2AALDH1A1MEN1
SCHEMBL10489384 0.83 KAT2B (0.74) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL8749218 0.83 KMT2A (0.62) KAT2BLMNAKMT2ATSHRTDP1
SCHEMBL6896833 0.83 KMT2A (0.62) KAT2BLMNAKMT2ATSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0999823-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 2000-05-17 EP claimed
WO-1999020235-A1 COMPOSITION FOR DYEING KERATIN FIBRES AND DYEING METHOD USING SAME L'OREAL (FR) 1999-04-29 WO claimed
EP-2263642-B1 Colouring bleaches HENKEL AG & CO KGAA (DE) 2020-04-15 EP disclosed
EP-2930126-B1 Fashionable aerosol dye HENKEL AG & CO KGAA (DE) 2019-10-09 EP disclosed
EP-2306963-B1 MATTING ADDITIVE FOR BLEACHING HENKEL AG & CO KGAA (DE) 2018-03-28 EP disclosed
EP-2044977-B1 Hair dye with oxidative pre-treatment HENKEL AG & CO KGAA (DE) 2018-02-14 EP disclosed
EP-2324811-B1 Foam-like dye HENKEL AG & CO KGAA (DE) 2018-01-03 EP disclosed
EP-2802383-B1 USE OF PROPYLENE OXIDE-MODIFIED STARCH FOR IMPROVING ARTIFICIAL COLOURING OF KERATIN FIBRES HENKEL AG & CO KGAA (DE) 2018-01-03 EP disclosed
EP-2320864-B1 HAIR PREPARATION COMPRISING CHITOSAN SUCCINAMIDE HENKEL AG & CO KGAA (DE) 2017-08-16 EP disclosed
US-9693937-B2 Foil applicator HENKEL AG & CO. KGAA (DE) 2017-07-04 US disclosed
EP-2424491-B1 FILM FORMER IN HAIR COLOURS HENKEL AG & CO KGAA (DE) 2017-05-24 EP disclosed
EP-1328244-A1 AGENT AND METHOD FOR COLOURING KERATIN FIBRES Wella Aktiengesellschaft (DE) 2003-07-23 EP disclosed
US-20030070239-A1 Agent and method for dyeing keratin fibers HFC PRESTIGE INTERNATIONAL OPERATIONS SWITZERLAND SÀRL (CH) 2003-04-17 US disclosed
US-6485529-B1 Agent and method for coloring fibers WELLA AKTIENGESELLSCHAFT (DE) 2002-11-26 US disclosed
WO-2002067882-A1 HAIR COLORANT IN THE FORM OF A CREAMY PERMANENT MOUSSE OR A STABLE FOAMED CREME COLORANT WELLA AKTIENGESELLSCHAFT (DE) 2002-09-06 WO disclosed
WO-2002022093-A1 AGENT AND METHOD FOR COLOURING KERATIN FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2002-03-21 WO disclosed
EP-1143923-A1 AGENT AND METHOD FOR COLOURING FIBRES Wella Aktiengesellschaft (DE) 2001-10-17 EP disclosed
US-6231622-B1 MIXTURES; BLUE COLOR WELLA AKTIENGESELLSCHAFT (DE) 2001-05-15 US disclosed
WO-2001028507-A1 AGENT AND METHOD FOR COLOURING FIBRES WELLA AKTIENGESELLSCHAFT (DE) 2001-04-26 WO disclosed
EP-1002516-A1 Hair dyes containing indan derivatives Wella Aktiengesellschaft (DE) 2000-05-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030070239-A1 Agent and method for dyeing keratin fibers KRT18, AOC1, S100B KAT2B 77/4885LMNA 828/4885KMT2A 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.