Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.32 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11042080 | 0.86 | MAPK1 (0.43) | KDM4EALDH1A1LMNAMAPTMEN1 | |
| SCHEMBL11041265 | 0.85 | ALDH1A1 (0.39) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL11080600 | 0.82 | KDM4E (0.42) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL11040186 | 0.78 | KDM4E (0.40) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL11040733 | 0.78 | KDM4E (0.36) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL11043189 | 0.72 | ALDH1A1 (0.42) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL10982606 | 0.69 | HSP90AA1 (0.49) | KDM4ERECQLALDH1A1POLBLMNA | |
| SCHEMBL10985368 | 0.68 | ALDH1A1 (0.41) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL10987800 | 0.67 | KDM4E (0.41) | KDM4ERECQLALDH1A1POLBNPSR1 | |
| SCHEMBL11037856 | 0.66 | KDM4E (0.39) | KDM4ERECQLALDH1A1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | claimed |
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |