Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11037859 | 0.88 | KDM4E (0.39) | KDM4ERECQLNPSR1S1PR1ALDH1A1 | |
| SCHEMBL11037856 | 0.88 | KDM4E (0.39) | KDM4ERECQLNPSR1S1PR1ALDH1A1 | |
| SCHEMBL11040290 | 0.83 | KDM4E (0.40) | KDM4ERECQLNPSR1S1PR1ALDH1A1 | |
| SCHEMBL11039854 | 0.82 | KDM4E (0.37) | KDM4ERECQLNPSR1ALDH1A1GAA | |
| SCHEMBL11039841 | 0.78 | KDM4E (0.40) | KDM4ERECQLNPSR1ALDH1A1POLB | |
| SCHEMBL11043402 | 0.77 | TSHR (0.43) | KDM4ERECQLS1PR1ALDH1A1POLB | |
| SCHEMBL11043453 | 0.75 | MEN1 (0.41) | KDM4ERECQLS1PR1ALDH1A1POLB | |
| SCHEMBL11081558 | 0.73 | ALDH1A3 (0.37) | KDM4ERECQLNPSR1S1PR1ALDH1A1 | |
| SCHEMBL11167920 | 0.73 | CHRM1 (0.40) | KDM4ERECQLALDH1A1POLBGAA | |
| SCHEMBL11042050 | 0.72 | S1PR1 (0.37) | KDM4ERECQLS1PR1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | claimed |
| EP-0107620-A1 | Phenol derivatives | CIBA-GEIGY AG (CH) | 1984-05-02 | — | — | EP | disclosed |