Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10779883 | 0.76 | MAPK1 (0.40) | NPC1ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL11148429 | 0.75 | MAPK1 (0.33) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL21673240 | 0.72 | MEN1 (0.36) | ALDH1A1KMT2AMEN1LMNARAB9A | |
| SCHEMBL12068348 | 0.72 | MAPK1 (0.58) | NPC1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL12068346 | 0.72 | MAPK1 (0.58) | NPC1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL258654 | 0.72 | MAPK1 (0.41) | NPC1ALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL13246730 | 0.69 | ALDH1A1 (0.69) | NPC1ALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL1562816 | 0.69 | MEN1 (0.40) | ALDH1A1KMT2AMEN1RAB9AL3MBTL1 | |
| SCHEMBL7473188 | 0.69 | PDGFRB (0.36) | KMT2AMEN1RAB9AADORA1MAPK1 | |
| SCHEMBL6047363 | 0.68 | NPC1 (0.72) | NPC1ALDH1A1KMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0041615-B1 | USE OF IMIDAZOLYL-VINYL KETONES AND ALCOHOLS AS ANTIMICROBIAL AGENTS | BAYER AG (DE) | 1984-02-22 | — | — | EP | disclosed |
| EP-0040366-B1 | IMIDAZOLYL-VINYL KETONES AND CARBINOLS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FUNGICIDES | BAYER AG (DE) | 1983-11-02 | — | — | EP | disclosed |
| US-4385061-A | Combating fungi with imidazolyl-vinyl ketones and carbinols | BAYER AKTIENGESELLSCHAFT (DE) | 1983-05-24 | — | — | US | disclosed |
| EP-0048827-A1 | Substituted 2,4-dichlorophenyl-imidazolyl-vinyl ketones, processes for their preparation and antimicrobial agents containing these compounds | BAYER AG (DE) | 1982-04-07 | — | — | EP | disclosed |
| EP-0041615-A1 | Use of imidazolyl-vinyl ketones and alcohols as antimicrobial agents | BAYER AG (DE) | 1981-12-16 | — | — | EP | disclosed |
| EP-0040366-A1 | Imidazolyl-vinyl ketones and carbinols, process for their preparation and their use as fungicides | BAYER AG (DE) | 1981-11-25 | — | — | EP | disclosed |