Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 3/20 | 0.31 |
| ▸ | USP5 | P45974 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | MTOR | P42345 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11041821 | 0.99 | DUSP10 (0.33) | DUSP10PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11249911 | 0.84 | BCHE (0.37) | BCHEKMT2A | |
| SCHEMBL11038147 | 0.84 | USP5 (0.35) | DUSP10PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11251660 | 0.83 | BCHE (0.38) | BCHEKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11037314 | 0.83 | USP5 (0.34) | DUSP10PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11357746 | 0.83 | BCHE (0.37) | BCHEKMT2A | |
| SCHEMBL11038211 | 0.83 | PDE4A (0.41) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL11037970 | 0.82 | LMNA (0.33) | DUSP10LMNABCHEALDH1A1SMN1; SMN2 | |
| SCHEMBL11038010 | 0.82 | TLR7 (0.42) | PDE4APDE4BPDE4CPDE4DLMNA | |
| Hydrochloric Acid SCHEMBL11036638 | 0.82 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038528-B1 | DIHYDRO-AS-TRIAZINO(5,6-C)QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1984-08-08 | — | — | EP | disclosed |
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | disclosed |