Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RHOC | P08134 | 1/20 | 0.38 |
| ▸ | RHOA | P61586 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9799924 | 1.00 | L3MBTL1 (0.43) | L3MBTL1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9799575 | 0.87 | PLOD2 (0.41) | RAB9ASMN1; SMN2NPC1HTTLMNA | |
| SCHEMBL11038316 | 0.87 | PLOD2 (0.41) | RAB9ASMN1; SMN2NPC1HTTLMNA | |
| SCHEMBL9799689 | 0.85 | L3MBTL1 (0.43) | L3MBTL1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9799633 | 0.83 | PARP1 (0.46) | RAB9ASMN1; SMN2NPC1ALDH1A1TDP1 | |
| SCHEMBL10668548 | 0.80 | SMN1; SMN2 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1TDP1MAPT | |
| SCHEMBL11525215 | 0.80 | L3MBTL1 (0.49) | L3MBTL1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10673355 | 0.78 | L3MBTL1 (0.40) | L3MBTL1SMN1; SMN2ALDH1A1TDP1MAPT | |
| SCHEMBL11406624 | 0.77 | NPC1 (0.52) | L3MBTL1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL10668466 | 0.77 | MAPT (0.35) | L3MBTL1SMN1; SMN2ALDH1A1TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0094348-B1 | OXIME ETHERS, PROCESS FOR THEIR PREPARATION, AGENTS CONTAINING THE OXIME ETHERS AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-07-24 | — | — | EP | claimed |