SCHEMBL11040256

SCHEMBL11040256

C[S+]([O-])c1nc(N)nc(Cl)c1N

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ADORA2A P29274 1/20 0.31
ADORA1 P30542 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10327545 0.72 NUDT1 (0.36)
SCHEMBL653958 0.71 MEN1 (0.44) ADORA2AADORA1
SCHEMBL10952766 0.71 ADORA2A (0.31) ADORA2AADORA1
SCHEMBL21894190 0.68 BCL6 (0.38) ADORA1
SCHEMBL9178364 0.66 KDM4E (0.40) ADORA2AADORA1
Dimethyl Sulfoxide SCHEMBL28387533 0.66 LMNA (0.39) ADORA2AADORA1
SCHEMBL29419387 0.64 DPP4 (0.35) ADORA2AADORA1
SCHEMBL1512060 0.64 DPP4 (0.35) ADORA2AADORA1
Hydrochloric Acid SCHEMBL1512064 0.62 DPP4 (0.34) ADORA2AADORA1
SCHEMBL4287559 0.61 PDE10A (0.44) ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0080917-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIO-PYRIMIDINE DERIVATIVES AND PYRIDATE, AND PROCESS FOR THE TREATMENT OF CORPS WITH THE AID OF SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1985-01-23 EP claimed
EP-0080917-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthio-pyrimidine derivatives and pyridate, and process for the treatment of corps with the aid of said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-06-08 EP claimed
EP-0080917-B1 HERBICIDAL COMPOSITIONS BASED ON 4-AMINO-6-CHLORO-5-ALKYLTHIO-PYRIMIDINE DERIVATIVES AND PYRIDATE, AND PROCESS FOR THE TREATMENT OF CORPS WITH THE AID OF SAID COMPOSITIONS P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1985-01-23 EP disclosed
EP-0080917-A1 Herbicidal compositions based on 4-amino-6-chloro-5-alkylthio-pyrimidine derivatives and pyridate, and process for the treatment of corps with the aid of said compositions P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1983-06-08 EP disclosed
EP-0027075-A1 5-Alkylsulfinyl pyrimidines, process for their preparation and their uses as herbicides P C U K PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1981-04-15 EP disclosed