SCHEMBL1104033

SCHEMBL1104033

CCC(C)(C)C(=O)NCCOOCCCC(=O)O

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 3/20 0.40
ADRA1A P35348 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HIF1A Q16665 1/20 0.35
TSHR P16473 1/20 0.34
ALDH1A1 P00352 2/20 0.33
DRD2 P14416 2/20 0.33
DRD4 P21917 2/20 0.33
PLA2G2A P14555 1/20 0.33
AKR1B1 P15121 1/20 0.33
PLA2G4A P47712 1/20 0.33
PRMT1 Q99873 1/20 0.33
EPHX2 P34913 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25767915 0.80 ADRA1A (0.56) ADRA1AMEN1KMT2ATSHRALDH1A1
SCHEMBL19725744 0.80 ADRA1A (0.56) ADRA1AMEN1KMT2ATSHRALDH1A1
SCHEMBL1104148 0.80 RIPK1 (0.36) RIPK1MEN1KMT2ADRD2DRD4
SCHEMBL11941707 0.79 RIPK1 (0.49) RIPK1ADRA1AMEN1KMT2AALDH1A1
SCHEMBL10123422 0.78 RIPK1 (0.40) RIPK1ADRA1ATSHRALDH1A1DRD2
SCHEMBL1104099 0.75 RIPK1 (0.36) RIPK1DRD2DRD4
SCHEMBL1104097 0.75 RIPK1 (0.36) RIPK1DRD2DRD4
SCHEMBL1104036 0.75 RIPK1 (0.37) RIPK1DRD2DRD4
SCHEMBL13219560 0.75 EPHX2 (0.41) RIPK1ADRA1ADRD2DRD4EPHX2
SCHEMBL13133423 0.74 RIPK1 (0.43) RIPK1MEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-8110337-B2 Mixture of binder, an unsaturated compound and acid generator; lithography FUJIFILM CORPORATION (JP) 2012-02-07 US disclosed
US-8012671-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-09-06 US disclosed
US-7989140-B2 Curable composition, image forming material, and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-08-02 US disclosed
US-7964334-B2 Mixture containing urea compound as photoinitiator; curing by exposure to laser light FUJIFILM CORPORATION (JP) 2011-06-21 US disclosed
US-7955781-B2 Negative-working photosensitive material and negative-working planographic printing plate precursor FUJIFILM CORPORATION (JP) 2011-06-07 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-7820357-B2 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2010-10-26 US disclosed
US-7723011-B2 Support, protective layer of crosslinked polymer ionically crosslinkable; ethylenically unsaturated polymerization initiator, binder polymer, dye; direct plate-making negative-working lithographic printing plate precursor; directly making a plate with a laser from a digital signal of a computer FUJIFILM CORPORATION (JP) 2010-05-25 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-20080145782-A1 IMAGE RECORDING MATERIAL AND NOVEL COMPOUND FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
US-20080057439-A1 Image recording material FUJIFILM CORPORATION (JP) 2008-03-06 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-20070298351-A1 IMAGE RECORDING MATERIAL, PLANOGRAPHIC PRINTING PLATE PRECURSOR, AND PLANOGRAPHIC PRINTING METHOD USING THE SAME FUJIFILM CORPORATION (JP) 2007-12-27 US disclosed
US-7291443-B2 Polymerizable composition and image-recording material using the same FUJIFILM CORPORATION (JP) 2007-11-06 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-7279266-B2 Photosensitive composition and lithographic printing plate precursor using the same FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-20070231739-A1 Polymerizable negative planographic printing plate precursor, stack of planographic printing plate precursors, and method of producing polymerizable negative planographic printing plate precursor FUJIFILM CORPORATION (JP) 2007-10-04 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070148593-A1 Polymerizable composition and planographic printing plate precursor using the same FUJIFILM CORPORATION 2007-06-28 US disclosed