Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.58 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.52 |
| ▸ | PI4KA | P42356 | 2/20 | 0.51 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.51 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.51 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.51 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.46 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.46 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.46 |
| ▸ | GAPDH | P04406 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | STAT6 | P42226 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19692161 | 1.00 | ADORA2A (0.58) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL28156591 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL1078828 | 0.91 | ADORA2A (0.64) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL8943715 | 0.90 | ADORA2A (0.57) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL5554234 | 0.89 | ADORA2A (0.56) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL9054202 | 0.88 | ADORA2A (0.55) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL8943868 | 0.87 | ADORA2A (0.53) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL8943541 | 0.85 | ADORA2A (0.55) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL8943533 | 0.85 | ADORA2A (0.53) | ADORA2AADORA3PI4KAPI4K2BPI4K2A | |
| SCHEMBL25408738 | 0.84 | ADORA2A (0.52) | ADORA2AADORA3PI4KAPI4K2BPI4K2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3266784-A1 | PROTEIN ARGININE N-METHYLTRANSFERASES INHIBITORS AND USES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2018-01-10 | — | — | EP | disclosed |
| WO-2017211958-A1 | PROTEIN ARGININE N-METHYLTRANSFERASES INHIBITORS AND USES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2017-12-14 | — | — | WO | disclosed |
| EP-0037310-B1 | SUBSTITUTED DEOXYADENOSINE DERIVATIVES | MERRELL TORAUDE ET COMPAGNIE (FR) | 1984-05-09 | — | — | EP | disclosed |
| US-4374128-A | TREATING RAPID CELL PROLIFERATION | MERRELL TORAUDE ET COMPAGNIE (FR) | 1983-02-15 | — | — | US | disclosed |
| EP-0037310-A1 | Substituted deoxyadenosine derivatives | MERRELL TORAUDE ET COMPAGNIE (FR) | 1981-10-07 | — | — | EP | disclosed |