SCHEMBL11040379

SCHEMBL11040379

CCN1/C(=C2\C(=O)N(c3ccc(S(=O)(=O)O)cc3)N=C2C)Sc2ccccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 8/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.45
▸ KAT8 Q9H7Z6 1/20 0.45
▸ MEN1 O00255 10/20 0.43
▸ KMT2A Q03164 10/20 0.43
▸ MAPT P10636 7/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ NPC1 O15118 1/20 0.43
▸ POLB P06746 3/20 0.42
▸ MMP13 P45452 1/20 0.42
▸ HPGD P15428 3/20 0.41
▸ HSD17B10 Q99714 2/20 0.41
▸ GFER P55789 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ LMNA P02545 1/20 0.39
▸ ALOX15 P16050 1/20 0.39
▸ ALOX12 P18054 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ CASP7 P55210 1/20 0.39
▸ GAA P10253 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11040384 1.00 ALDH1A1 (0.45) ALDH1A1NPSR1KAT8MEN1KMT2A
SCHEMBL9622414 0.87 MAPT (0.53) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL10036143 0.82 KAT8 (0.49) ALDH1A1KAT8MEN1KMT2AMAPT
SCHEMBL10036082 0.79 MAPT (0.45) ALDH1A1KAT8MEN1KMT2AMAPT
SCHEMBL11587183 0.79 MAPT (0.45) ALDH1A1KAT8MEN1KMT2AMAPT
SCHEMBL9156158 0.79 MAPT (0.55) ALDH1A1MEN1KMT2AMAPTPOLB
Potassium Ion SCHEMBL9155095 0.77 KDM4E (0.44) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL9622105 0.76 MAPT (0.50) ALDH1A1NPSR1MEN1KMT2AMAPT
SCHEMBL14063194 0.74 MEN1 (0.39) ALDH1A1NPSR1KAT8MEN1KMT2A
SCHEMBL9622698 0.72 ALDH1A1 (0.50) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4439520-A Sensitized high aspect ratio silver halide emulsions and photographic elements EASTMAN KODAK COMPANY (US) 1984-03-27 — — US disclosed
US-4304769-A PESTICIDES EASTMAN KODAK COMPANY (US) 1981-12-08 — — US disclosed
US-4247627-A Photographic elements having hydrophilic colloid layers containing hydrophobic ultraviolet absorbers uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1981-01-27 — — US disclosed
US-4214047-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-07-22 — — US disclosed
US-4203716-A Photographic elements having hydrophilic colloid layers containing hydrophobic addenda uniformly loaded in latex polymer particles EASTMAN KODAK COMPANY (US) 1980-05-20 — — US disclosed
US-4199363-A Processes for achieving uniform, efficient distribution of hydrophobic materials through hydrophilic colloid layers and loaded latex compositions EASTMAN KODAK COMPANY (US) 1980-04-22 — — US disclosed
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