Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 4/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 5/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040511 | 0.85 | CA2 (0.60) | HTR2CHTR2ACA2MAPTTSHR | |
| SCHEMBL11040283 | 0.84 | CA2 (0.47) | HTR2CHTR2BHTR2ACA2TSHR | |
| SCHEMBL11040237 | 0.84 | CA2 (0.59) | HTR2CHTR2ACA2MAPTTSHR | |
| SCHEMBL11040233 | 0.84 | CA2 (0.59) | HTR2CHTR2ACA2MAPTTSHR | |
| SCHEMBL11040310 | 0.81 | CA2 (0.51) | HTR2CHTR2BHTR2ACA2MAPT | |
| SCHEMBL10546481 | 0.78 | CA2 (0.40) | CA2PPARGPPARDPPARA | |
| SCHEMBL11038153 | 0.70 | CA2 (0.43) | CA2MAPTMEN1KMT2APPARG | |
| SCHEMBL11044359 | 0.70 | CA2 (0.43) | CA2PPARGPPARDPPARA | |
| SCHEMBL11043516 | 0.70 | CA2 (0.62) | CA2MAPTGAATSHRKMT2A | |
| SCHEMBL10546613 | 0.69 | CA2 (0.48) | CA2TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448971-A | Hypoglycemic 5-phenyl-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1984-05-15 | — | — | US | disclosed |
| US-4407811-A | Hypoglycemic 5-substituted oxazolidine-2,4-diones | PFIZER INC. (US) | 1983-10-04 | — | — | US | disclosed |
| US-4399296-A | TRIMETHYLSILYL CYANOHYDRIN INTERMEDIATES | PFIZER INC. (US) | 1983-08-16 | — | — | US | disclosed |
| US-4367234-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1983-01-04 | — | — | US | disclosed |