Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040717 | 1.00 | TSHR (0.44) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL28723430 | 0.87 | TERT (0.31) | MAPTLMNAUSP2RECQLTDP1 | |
| SCHEMBL28240702 | 0.81 | — | — | |
| SCHEMBL11122649 | 0.75 | FAAH (0.50) | MAPTLMNAUSP2RECQLTDP1 | |
| SCHEMBL18270282 | 0.75 | FAAH (0.50) | MAPTLMNAUSP2RECQLTDP1 | |
| SCHEMBL11122653 | 0.75 | FAAH (0.50) | MAPTLMNAUSP2RECQLTDP1 | |
| SCHEMBL18270292 | 0.75 | FAAH (0.50) | MAPTLMNAUSP2RECQLTDP1 | |
| SCHEMBL5436303 | 0.74 | TSHR (0.53) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL5436307 | 0.74 | TSHR (0.53) | TSHRALDH1A1MAPTABCC4LMNA | |
| SCHEMBL5951829 | 0.74 | F7 (0.41) | TSHRALDH1A1MAPTLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4454243-A | REACTING LITHIUM AND AN ALKENE USING A TRANSITION OR ALKALI METAL COMPLEX | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1984-06-12 | — | — | US | disclosed |
| EP-0015541-B1 | PROCESS FOR THE PREPARATION OF ORGANOLITHIUM COMPOUNDS BESIDES LITHIUM HYDRIDE; CATALYSTS | Studiengesellschaft Kohle mbH (DE) | 1984-03-07 | — | — | EP | disclosed |
| US-4354982-A | Production of organolithium compounds and lithium hydride | STUDIENGESELLSCHAFT KOHLE M.B.H. (DE) | 1982-10-19 | — | — | US | disclosed |
| EP-0015541-A2 | Process for the preparation of organolithium compounds besides lithium hydride; catalysts | Studiengesellschaft Kohle mbH (DE) | 1980-09-17 | — | — | EP | disclosed |