Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 6/20 | 0.44 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.33 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040792 | 0.88 | KCNH2 (0.51) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11041776 | 0.87 | NR1I2 (0.43) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11038925 | 0.86 | KCNH2 (0.44) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11045887 | 0.84 | NR1I2 (0.64) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11045889 | 0.84 | NR1I2 (0.64) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11038988 | 0.83 | NR1I2 (0.53) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11179688 | 0.83 | NR1I2 (0.53) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11038993 | 0.83 | NR1I2 (0.53) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11038984 | 0.83 | NR1I2 (0.53) | NR1I2PPARGPGRESR1TDP1 | |
| SCHEMBL11040357 | 0.82 | KCNH2 (0.47) | NR1I2PPARGPGRESR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0027599-B1 | CEPHEM COMPOUNDS, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-03 | — | — | EP | disclosed |