SCHEMBL1104089

SCHEMBL1104089

C=CCOOCCCCOC(=O)C(C)(C)CC

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.35
HPGD P15428 1/20 0.35
CYP3A4 P08684 2/20 0.34
ALDH1A1 P00352 1/20 0.34
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
THRB P10828 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1104083 0.90 THRB (0.35) TSHRHPGDCYP3A4CYP4F2CYP4A11
SCHEMBL1104107 0.82 LPAR3 (0.43) TSHRHPGDCYP3A4ALDH1A1CYP4F2
SCHEMBL13667082 0.81 CYP4F2 (0.42) TSHRHPGDALDH1A1CYP4F2CYP4A11
SCHEMBL13561225 0.81 LPAR3 (0.46) TSHRHPGDCYP3A4ALDH1A1CYP4F2
SCHEMBL14368441 0.80 ACHE (0.40)
SCHEMBL274605 0.80 CYP4F2 (0.37) TSHRHPGDCYP3A4ALDH1A1CYP4F2
SCHEMBL750654 0.79 TSHR (0.43) TSHRHPGDCYP3A4ALDH1A1CYP4F2
SCHEMBL13667073 0.79 CYP4F2 (0.46) TSHRCYP3A4ALDH1A1CYP4F2CYP4A11
SCHEMBL12793066 0.79 TSHR (0.60) TSHRHPGDCYP3A4ALDH1A1CYP4F2
SCHEMBL1104103 0.79 THRB (0.42) TSHRHPGDALDH1A1CYP4F2CYP4A11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8151705-B2 Method of preparing lithographic printing plate FUJIFILM CORPORATION (JP) 2012-04-10 US disclosed
US-7883827-B2 acrylate copolymer binder has superior developing properties while suppressing damages resulting from permeation of the developer caused by the acid content; for use with a laser beam; excellent in printing durability and image formation FUJIFILM CORPORATION (JP) 2011-02-08 US disclosed
US-20100081771-A1 METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE FUJIFILM CORPORATION (JP) 2010-04-01 US disclosed
US-7507525-B2 Polymerizable composition and lithographic printing plate precursor FUJIFILM CORPORATION (JP) 2009-03-24 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-7279539-B2 Alkali-soluble polymer and polymerizable composition thereof FUJIFILM CORPORATION (JP) 2007-10-09 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed