Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.36 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | LPAR6 | P43657 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25516001 | 0.90 | THRB (0.40) | THRBTSHRLPAR1LPAR4LPAR5 | |
| SCHEMBL12565572 | 0.87 | THRB (0.48) | THRBTSHRLPAR5HPGDALDH1A1 | |
| SCHEMBL1104109 | 0.86 | TSHR (0.49) | THRBTSHRLPAR1LPAR4LPAR5 | |
| SCHEMBL25784302 | 0.84 | THRB (0.49) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL25784313 | 0.84 | THRB (0.49) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL25863843 | 0.83 | TSHR (0.41) | THRBTSHRLPAR1LPAR4LPAR5 | |
| SCHEMBL1104101 | 0.82 | TSHR (0.40) | THRBTSHRLPAR1LPAR4LPAR5 | |
| SCHEMBL749916 | 0.80 | THRB (0.57) | THRBTSHRHPGDALDH1A1TP53 | |
| SCHEMBL3412116 | 0.80 | TSHR (0.53) | TSHRLPAR1LPAR4LPAR5LPAR2 | |
| SCHEMBL13557205 | 0.78 | DGKA (0.45) | TSHRALDH1A1HSD17B10DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8151705-B2 | Method of preparing lithographic printing plate | FUJIFILM CORPORATION (JP) | 2012-04-10 | — | — | US | disclosed |
| US-20100081771-A1 | METHOD OF PREPARING LITHOGRAPHIC PRINTING PLATE | FUJIFILM CORPORATION (JP) | 2010-04-01 | — | — | US | disclosed |