Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 9/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11023886 | 0.88 | TRPA1 (0.47) | HTR2ASLC6A4CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9814747 | 0.84 | SCN9A (0.39) | HTR2ASLC6A4KCNH2ARMAPT | |
| SCHEMBL9814890 | 0.84 | SCN9A (0.39) | HTR2ASLC6A4KCNH2ARMAPT | |
| SCHEMBL10906720 | 0.77 | SLC6A4 (0.36) | HTR2ASLC6A4KCNH2ARKDM4E | |
| SCHEMBL11110203 | 0.76 | TRPA1 (0.46) | ARMAPTMEN1ALDH1A1CYP2D6 | |
| SCHEMBL23120412 | 0.75 | SLC6A4 (0.41) | HTR2ASLC6A4KCNH2ARMAPT | |
| SCHEMBL23120390 | 0.74 | PPARG (0.41) | HTR2ASLC6A4KCNH2ARMAPT | |
| SCHEMBL10906698 | 0.73 | ERBB2 (0.37) | HTR2ASLC6A4MAPTMEN1CYP1A2 | |
| SCHEMBL7200091 | 0.73 | DUT (0.37) | HTR2ASLC6A4ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL10745511 | 0.73 | DUT (0.37) | HTR2ASLC6A4ALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044139-B1 | NEW CYCLOPROPANECARBOXYLATES, THEIR PRODUCTION AND A LOW FISH TOXIC INSECTICIDE AND/OR ACARICIDE CONTAINING THEM AS AN ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-09-26 | — | — | EP | disclosed |
| US-4376785-A | Cyclopropanecarboxylates and a low fish toxic insecticide and/or acaricide containing them | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-03-15 | — | — | US | disclosed |
| EP-0044139-A2 | New cyclopropanecarboxylates, their production and a low fish toxic insecticide and/or acaricide containing them as an active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-01-20 | — | — | EP | disclosed |