Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CETP | P11597 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045964 | 0.81 | NR1I2 (0.53) | NR1I2ALDH1A1L3MBTL1POLB | |
| SCHEMBL11045403 | 0.78 | NR1I2 (0.45) | NR1I2KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL11041665 | 0.78 | NR1I2 (0.46) | NR1I2GAARELAAKR1C3PTGS2 | |
| SCHEMBL11044692 | 0.77 | NR1I2 (0.46) | NR1I2KDM4EALDH1A1POLBNPC1 | |
| SCHEMBL11045371 | 0.77 | NR1I2 (0.50) | NR1I2KDM4EALDH1A1 | |
| SCHEMBL10886960 | 0.77 | AKR1C3 (0.45) | RELAAKR1C3PTGS1KDM4EALDH1A1 | |
| SCHEMBL11040960 | 0.77 | AKR1C3 (0.45) | RELAAKR1C3PTGS1KDM4EALDH1A1 | |
| SCHEMBL28980681 | 0.76 | NR1I2 (0.41) | NR1I2GAACETPPTGS1PTGS2 | |
| SCHEMBL11046190 | 0.75 | KDM4E (0.47) | NR1I2GAAKDM4EALDH1A1L3MBTL1 | |
| SCHEMBL28362849 | 0.72 | NQO2 (0.46) | NR1I2GAARELAPTGS1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |