Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NEK2 | P51955 | 1/20 | 0.36 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045371 | 0.84 | NR1I2 (0.50) | NR1I2KMT2ALMNACYP2C9MEN1 | |
| SCHEMBL11045403 | 0.83 | NR1I2 (0.45) | NR1I2ALDH1A1MAPTMAOBNPC1 | |
| SCHEMBL11045964 | 0.83 | NR1I2 (0.53) | NR1I2KMT2ALMNAMEN1ALDH1A1 | |
| SCHEMBL11041665 | 0.82 | NR1I2 (0.46) | NR1I2KMT2ALMNACYP2C9MEN1 | |
| SCHEMBL11048410 | 0.77 | NR1I2 (0.42) | NR1I2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL11040968 | 0.77 | NR1I2 (0.46) | NR1I2ALDH1A1NPC1POLBKDM4E | |
| SCHEMBL11044689 | 0.73 | CYP2C9 (0.44) | NR1I2CYP2C9ALDH1A1MAOBGRIK1 | |
| SCHEMBL11044687 | 0.73 | CYP2C9 (0.44) | NR1I2CYP2C9ALDH1A1MAOBGRIK1 | |
| SCHEMBL11041660 | 0.72 | SMN1; SMN2 (0.41) | NR1I2KMT2ALMNAMEN1TDP1 | |
| SCHEMBL17289013 | 0.71 | SMN1; SMN2 (0.43) | NR1I2KMT2ALMNAMEN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4473560-A | Diphosphonic acid derivatives and pharmaceutical preparations containing them | SCHERING AKTIENGESELLSCHAFT (DE) | 1984-09-25 | — | — | US | disclosed |