Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641592 | 0.94 | MAPT (0.56) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7638488 | 0.86 | MAPT (0.46) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7642077 | 0.84 | ALDH1A1 (0.52) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11039782 | 0.84 | ALDH1A1 (0.39) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL2767092 | 0.83 | MAPT (0.69) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30197830 | 0.83 | MAPT (0.69) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL10799269 | 0.81 | MAPT (0.54) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11742719 | 0.80 | MAPT (0.49) | MAPTKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7636290 | 0.78 | ALDH1A1 (0.41) | MAPTALDH1A1LMNATSHRTDP1 | |
| SCHEMBL9873109 | 0.78 | RECQL (0.41) | MAPTKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4271072-A | FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES | AMERICAN HOECHST CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |