Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641592 | 0.91 | MAPT (0.56) | MAPTTAAR1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11041203 | 0.86 | MAPT (0.50) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL9872251 | 0.86 | CYP3A4 (0.45) | MAPTALDH1A1CYP3A4KMT2AMEN1 | |
| SCHEMBL7636019 | 0.84 | TSHR (0.43) | MAPTALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL7640487 | 0.84 | ESR1 (0.49) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL7642077 | 0.82 | ALDH1A1 (0.52) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL10797168 | 0.81 | MAPT (0.50) | MAPTTAAR1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL11715218 | 0.81 | MAPT (0.46) | MAPTTAAR1ALDH1A1CYP3A4KMT2A | |
| SCHEMBL7643742 | 0.80 | POLB (0.44) | MAPTALDH1A1KMT2AMEN1KDM4E | |
| SCHEMBL14691322 | 0.79 | ALDH1A1 (0.44) | MAPTALDH1A1KMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6464734-B1 | USED FOR DYEING OR PRINTING HYDROXYL AND/OR CARBOXAMIDO CONTAINING MATERIALS SUCH AS POLYVINYL ALCOHOL, POLYURETHANES AND POLYAMIDES; WASHFASTNESS | DYSTAR TEXTILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) | 2002-10-15 | — | — | US | disclosed |
| EP-1134260-A1 | Deep black dye mixtures of fiber-reactive azo dyes | DyStar Textilfarben GmbH & Co. Deutschland KG (DE) | 2001-09-19 | — | — | EP | disclosed |
| US-4430259-A | Water-soluble disazo compounds suitable as fiber-reactive dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-02-07 | — | — | US | disclosed |
| US-4283196-A | FIXING BY ACTION OF AN ALKALINE AGENT | AMERICAN HOECHST CORPORATION (US) | 1981-08-11 | — | — | US | disclosed |
| US-4271072-A | FIBER-REACTIVE, FOR DYEING NATURAL AND SYNTHETIC POLYAMIDES AND CELULOSES | AMERICAN HOECHST CORPORATION (US) | 1981-06-02 | — | — | US | disclosed |