Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11040626 | 0.95 | TSHR (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28447019 | 0.86 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11137061 | 0.84 | TSHR (0.56) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL15715 | 0.84 | THRB (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL15941866 | 0.84 | THRB (0.48) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11038043 | 0.83 | TSHR (0.46) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL28239747 | 0.82 | THRB (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| Methane SCHEMBL27947537 | 0.82 | THRB (0.47) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11041981 | 0.82 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL28445117 | 0.82 | TSHR (0.61) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446175-A | ACRYLATE, CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-01 | — | — | US | claimed |
| US-4436885-A | Preparation of isocyanate-functional polymers containing a terminal monosulfide group | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-13 | — | — | US | claimed |
| US-4351755-A | MOISTURE CURABLE COATINGS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-28 | — | — | US | claimed |