Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.32 |
| ▸ | RAD52 | P43351 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041234 | 0.82 | TSHR (0.53) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL11039648 | 0.79 | TSHR (0.53) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL11040626 | 0.78 | TSHR (0.48) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL11137061 | 0.77 | TSHR (0.56) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL181712 | 0.77 | TSHR (0.59) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL2483259 | 0.77 | TSHR (0.59) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL5362558 | 0.77 | TSHR (0.59) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL2481162 | 0.77 | TSHR (0.59) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL17780845 | 0.77 | TSHR (0.59) | TSHRHTTPOLBAPEX1TDP1 | |
| SCHEMBL1850039 | 0.77 | TSHR (0.59) | TSHRHTTPOLBAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4446175-A | ACRYLATE, CHAIN TRANSFER | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-05-01 | — | — | US | claimed |
| US-4436885-A | Preparation of isocyanate-functional polymers containing a terminal monosulfide group | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-13 | — | — | US | claimed |
| US-4351755-A | MOISTURE CURABLE COATINGS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1982-09-28 | — | — | US | claimed |