Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041289 | 1.00 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL10911756 | 0.96 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL10911765 | 0.96 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL10911746 | 0.96 | ALDH1A1 (0.65) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL10784727 | 0.90 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL10784722 | 0.90 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL11041837 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL11041834 | 0.89 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL27942150 | 0.88 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL1962635 | 0.87 | MAPT (0.54) | ALDH1A1MAPTLMNACYP2C9MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59144728-A | — | — | None | — | — | JP | disclosed |
| EP-0118046-A1 | Liquid crystal compounds, liquid crystal compositions and liquid crystal display devices | HITACHI, LTD. (JP) | 1984-09-12 | — | — | EP | disclosed |
| JP-S59144728-A | LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY ELEMENT | HITACHI LTD | 1984-08-18 | — | — | JP | disclosed |