Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11041837 | 1.00 | ALDH1A1 (0.56) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL10784722 | 0.99 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL10784727 | 0.99 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL1962635 | 0.95 | MAPT (0.54) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL21482740 | 0.93 | MGLL (0.52) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL11041289 | 0.89 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL11041282 | 0.89 | ALDH1A1 (0.70) | ALDH1A1MAPTLMNACYP2C9MEN1 | |
| SCHEMBL12125150 | 0.89 | MAPT (0.49) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL12125147 | 0.89 | MAPT (0.49) | ALDH1A1MAPTLMNACYP2C9GRM2 | |
| SCHEMBL12125148 | 0.89 | MAPT (0.49) | ALDH1A1MAPTLMNACYP2C9GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0118046-A1 | Liquid crystal compounds, liquid crystal compositions and liquid crystal display devices | HITACHI, LTD. (JP) | 1984-09-12 | — | — | EP | disclosed |