Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.65 |
| ▸ | HMGCR | P04035 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | FYN | P06241 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TPMT | P51580 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10995824 | 0.85 | HSD17B10 (0.46) | HSD17B10HMGCRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10994734 | 0.83 | KDM4E (0.54) | HSD17B10HMGCRL3MBTL1AKR1C4AKR1C3 | |
| SCHEMBL27803206 | 0.83 | HMGCR (0.51) | HSD17B10HMGCRL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7813490 | 0.79 | HSD17B10 (1.00) | HSD17B10LCKFYNAKR1C4AKR1C3 | |
| SCHEMBL10712789 | 0.77 | AKR1C3 (0.58) | HSD17B10HMGCRAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL30745046 | 0.77 | HSD17B10 (0.71) | HSD17B10LCKFYNKDM4EALDH1A1 | |
| SCHEMBL8545309 | 0.77 | HSD17B10 (0.71) | HSD17B10LCKFYNAKR1C4AKR1C3 | |
| SCHEMBL1188761 | 0.77 | HSD17B10 (0.71) | HSD17B10LCKFYNKDM4EALDH1A1 | |
| SCHEMBL10355393 | 0.77 | HSD17B10 (0.71) | HSD17B10LCKFYNAKR1C4AKR1C3 | |
| SCHEMBL8980655 | 0.76 | APEX1 (0.49) | HSD17B10HMGCRKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0105484-A2 | 3-Propionylsalicyclic acid derivatives and process for the preparation of the same | Yamamoto Chemical Industrial Company, Limited (JP) | 1984-04-18 | — | — | EP | disclosed |