Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.45 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL633344 | 0.77 | HTT (0.54) | NPC1RAB9APGRMEN1KMT2A | |
| SCHEMBL251644 | 0.74 | ALDH1A1 (0.43) | EPHX1EPHX2MEN1KMT2AMAPT | |
| SCHEMBL27714137 | 0.71 | ALDH1A1 (0.55) | NPC1RAB9AEPHX1EPHX2MEN1 | |
| SCHEMBL8896647 | 0.71 | ALDH1A1 (0.41) | NPC1RAB9AMAPTTRPV1KDM4E | |
| SCHEMBL331059 | 0.71 | ALDH1A1 (0.59) | NPC1RAB9AEPHX1EPHX2MEN1 | |
| SCHEMBL14106777 | 0.71 | APEX1 (0.53) | NPC1RAB9AP2RY1EPHX1EPHX2 | |
| SCHEMBL30063430 | 0.70 | POLB (0.72) | NPC1RAB9AP2RY1EPHX1EPHX2 | |
| SCHEMBL11175842 | 0.70 | POLB (0.72) | NPC1RAB9AP2RY1EPHX1EPHX2 | |
| SCHEMBL623079 | 0.69 | HPGD (0.50) | NPC1RAB9APGRMAPTALDH1A1 | |
| SCHEMBL4068582 | 0.69 | HPGD (0.52) | NPC1RAB9AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478852-A | FUNGICIDES | CELAMERCK GMBH & CO. KG. (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4239888-A | 1-Phenyluracils | PFIZER INC. (US) | 1980-12-16 | — | — | US | disclosed |