Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 6/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.42 |
| ▸ | DRD4 | P21917 | 3/20 | 0.42 |
| ▸ | DRD3 | P35462 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6510351 | 0.91 | HPGD (0.52) | HPGDKMT2ALMNAMEN1FFAR1 | |
| SCHEMBL251644 | 0.84 | ALDH1A1 (0.43) | HPGDKMT2ALMNAMEN1TP53 | |
| SCHEMBL8896647 | 0.80 | ALDH1A1 (0.41) | HTTNPC1RAB9ATSHRMAPT | |
| SCHEMBL19411968 | 0.79 | ALDH1A1 (0.43) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL8622331 | 0.78 | MAPT (0.52) | HPGDKMT2AMEN1HTTNPC1 | |
| SCHEMBL7993466 | 0.78 | NPSR1 (0.52) | KMT2ALMNAMEN1HTTTP53 | |
| SCHEMBL28380438 | 0.77 | NPSR1 (0.41) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL10773638 | 0.76 | ALDH1A1 (0.59) | HPGDKMT2ALMNAMEN1HTT | |
| SCHEMBL8590182 | 0.74 | CA4 (0.54) | HPGDKMT2AMEN1HTTNPC1 | |
| SCHEMBL29288587 | 0.73 | LTA4H (0.50) | HPGDKMT2AMEN1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117881655-A | Ultraviolet radiation and visible radiation absorbing compounds | 爱尔克米亚公司 | 2024-04-12 | — | — | CN | disclosed |
| CN-102993250-B | -9-deoxidation-9A-azepine-9A-the a-homoerythromycin A derivatives that C-3 replaces | Luoyang Huizhong Animal Medicine Co., Ltd. (CN) | 2016-02-10 | — | — | CN | disclosed |
| CN-102993250-A | C-3 substituted-9-deoxidized-9A-aza-9A-high erythromycin A derivative | LUOYANG HUIZHONG ANIMAL MEDICINE CO LTD | 2013-03-27 | — | — | CN | disclosed |
| US-7495015-B2 | Indazole derivatives and methods for using the same | ROCHE PALO ALTO LLC (US) | 2009-02-24 | — | — | US | disclosed |
| EP-1747202-A1 | INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F.HOFFMANN-LA ROCHE AG (CH) | 2007-01-31 | — | — | EP | disclosed |
| US-20050215595-A1 | Indazole derivatives and methods for using the same | ROCHE PALO ALTO LLC | 2005-09-29 | — | — | US | disclosed |
| WO-2005085206-A1 | INDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | F. HOFFMANN-LA ROCHE AG (CH) | 2005-09-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050215595-A1 | Indazole derivatives and methods for using the same | MAPK1, MAP3K1, MAP3K7 | HPGD 614/4885KMT2A 2993/4885LMNA 2568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.