Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | HMOX1 | P09601 | 2/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11045644 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP11B1CYP11B2HMOX1TBXA2R | |
| SCHEMBL11044530 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP11B1CYP11B2HMOX1TBXA2R | |
| SCHEMBL10781903 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP11B1CYP11B2HMOX1TBXA2R | |
| SCHEMBL11043302 | 1.00 | TBXAS1 (0.47) | TBXAS1CYP11B1CYP11B2HMOX1TBXA2R | |
| SCHEMBL11047177 | 0.99 | TBXAS1 (0.44) | TBXAS1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL11041471 | 0.89 | CYP11B1 (0.41) | TBXAS1CYP11B1CYP11B2HMOX1 | |
| SCHEMBL10780768 | 0.89 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL10780558 | 0.89 | TBXAS1 (0.52) | TBXAS1 | |
| SCHEMBL10780718 | 0.89 | TBXAS1 (0.56) | TBXAS1 | |
| SCHEMBL10781022 | 0.89 | TBXAS1 (0.52) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4489087-A | Spermicidal thioketal substituted N-alkyl imidazoles | SYNTEX (U.S.A.) INC. (US) | 1984-12-18 | — | — | US | disclosed |